Eddie Van Halen Still Smoke

liver - the body's chemical factory

is the main organ responsible for the synthesis of substances for the body and the largest "chemical factory" of the human body. In the spiritual equivalent of the liver is the center of the physical transformation of matter. Many functions such as production and accumulation of energy and detoxify the body. Although it has a high regenerative capacity, it is exposed to many diseases. They are they are already well known, hence the large amount of drugs, mainly herbal, available in pharmacies.

Introduction

liver is the largest organ in our body, built from thousands of cells called hepatocytes. Plays an important role in the digestive system, excretory secretory and participating in the metabolism of fats, carbohydrates and proteins. Of particular importance is the generation of bile is necessary for digestion of fats and fibrinogen involved in the process of blood clotting. In addition, the liver stores iron and vitamins A, D, E, small amounts of B12 and C, which releases as necessary and, through the blood filtration, allows purification of the body of toxins and harmful waste products. Despite the enormous regenerative capacity of hepatocytes, they are too large reduces the load on physiological functions and the entire liver failure, which due to its functions performed, can have serious consequences for the whole of our body and even life-threatening.

Co. threatening liver and what steps should be taken to protect it?
Liver disease is one of the most common illnesses. Most of those affected are not even aware of the disease, until a very advanced stage. The first sign that the liver is broken we are bloating after meals, nausea, satiety, and stinging or pain on the right side of the abdomen under the ribs radiating up. The signs of chronic liver disease may include: weakness, fatigability, lack of appetite, skin lesions and anemia, and disorders blood clotting. Apart from this there may be menstrual disorders and fertility in women and in men decrease the potency and feminization symptoms (implying the presence of female characteristics in males such as changing body shape and appearance of the genitalia, increasing vocal range, as a result of a hormonal disorder) .

Causes of liver failure

show cause liver failure can be:

· poor diet (too rich and fatty food),

· alcohol abuse,

· abuse or chronic treatment of certain drugs (phenytoin, paracetamol, diclofenac, fluconazole, erythromycin, amiodarone, statins, ranitidine),

· ; environmental toxins (chlorine and heavy metals contaminating the water),

· viruses (viral - hepatitis - type A, B, C, E, cytomegalovirus),

· parasites (liver fluke),

· poisoning (toxins from fungi, rotten food).

prevention of liver diseases

Due to the fact that many of these factors can not completely eliminate, might be interested in prevention of liver diseases for which we include:

first Easily digestible diet, rich in coarse bread, fruits and vegetables that contain unsaturated fatty acids and vitamins.

second Reducing the number of fatty and fried dishes for stewed, boiled and baked.

third Meals eaten slowly, regularly (4-5 a day) and within a reasonable quantities.

4th Avoiding excess salt (for seasoning foods with herbs), spices and sugar (by replacing it with fruit and vegetable snacks).

5th Maintaining an appropriate weight for age and height or dropping excess weight.

6th Maintaining good hygiene, especially frequent hand washing, fruit and vegetables before consumption.

7th Reducing the amount of alcohol, coffee, carbonated drinks and smoking cessation.

8th Use only the necessary medicines, by the time needed to heal.

9th Control tests during pharmacotherapy (some antibiotics, oral contraceptives).

10.Stosowanie preparations containing building blocks of natural substances, to accelerate the regeneration and supporting the work of the liver.

remember that it is much easier to prevent liver disease than cure!


What ingredients include preparations used during liver ailment?
Favourable results in treatment and prevention of liver diseases can be achieved using drugs of natural origin.

include preparations containing:

extract from milk thistle seed Silybum marianum (L.) Gaertn .

milk thistle fruit Fructus Silybi Maria are pharmaceutical raw material. In the dry husk of the seed and pericarp of fruit plant accumulates silymarin [Cappelletti and Caniato]. Silymarin is the collective term flavonolignans group, ie compounds belonging to flavonoids. They are relatively rare in plants. The silymarin include: silybin in two isomeric forms A and B (a complex known as silibinin), izosylibina in two isomeric forms A and B (the so-called complex. izosylibininy) sylikrystyna (syn. sylichrystyna) and sylidianina (syn. sylidionina). Therapeutic effect in relation to the liver is mainly attributed sylibinie. There have also been other forms flavonolignans, such as 2.3-and 2.3-dehydrosylibina dehydrosylikrystyna and other flawonolignany, including sylimonina, sylandrina [Kohlmünzer, Morazzoni and Bombardelli]. Silymarin content of the fruit ranges from 1.0 to 3.3%. Milk cultivated in Poland contains 0.8-1.0% silybin, 0.6-0.9% sylikrystyny, izosylibiny 0.2-0.4%, 0.3-0.5% sylidianiny. In the initial stage of the production of silymarin pericarp is separated from the material Backup achenes. The supplementary material comes mainly fat (30%), protein (24%) and carbohydrates. The oil is dominated by linolenic acid (53%), belonging to the essential fatty acids (EFA). Among the predominant saturated fatty acid palmitic acid (8.5%). The basic amino acid protein is glutamic acid (18.2%). The share of essential amino acids is on average 29 g in 100 g of protein [Andrews and K. Sadowska]. In

Milk belongs to a group of medicinal plants, whose effects on the body human body is very well documented. Among herbal remedies, the largest market share medicines containing silymarin used in liver diseases. Flawonolignany exert antyhepatotoksyczne and protective to the liver. The mechanism of this action is based on stabilizing the membranes of hepatocytes and niedopuszczaniu to connect to the toxins from the cell surface. Presumably sylimarin influences stimulate liver cell ribosomal RNA and protein synthesis increases hepatocydowych. Silymarin leads to stabilization of mast cells, protects against radiation which causes inhibition of hepatic and splenic DNA and RNA [Morazzoni and Bombardelli]. Also exhibits antagonistic action in relation to the Amanita toxins sromotnikowego: falotoksyn and amatotoksyn [Kohlmünzer]. Detoxicates reflected a reduction of bilirubin in the blood and normalizing parameters (AST, ALT, GGT) [Fowler, Sadowska A.]. Preparations containing complex flavonolignans are recommended for long-term treatment of liver diseases caused by alcoholism, as well as in the treatment of viral hepatitis A, B and C. There are no side effects in the treatment of silymarin, even at high doses, is of particular importance in the treatment of chronic diseases liver [Hu et al.]. Liver poisoning may result from taking potent drugs such as cytotoxic drugs in cancer therapy, antiviral drugs to treat AIDS, and antibiotics. Silymarin may prevent liver dysfunction and alleviate side effects of drug therapy. Particularly important is the lack of interaction between silymarin and synthetic drugs [Hu et al.]. On grounds of cytoprotective activity, and anti-inflammatory antykancerogenną, sylimarin may have applications in dermatology and skin protection [Bhatia et al., Li et al.]. Preparations: SYLIMAROL, SYLITRAX, SYLIFLEX, SYLICYNAR, Verdin, SYLIVERIN .

herb artichoke extract

in the treatment of diseases associated with impaired functioning of the liver, sometimes as often used artichoke Cynara scolymus, a plant of the family Compositae complex. Green is a perennial plant, originally from North Africa - from Ethiopia, and later in Egypt - from whence it came to southern Europe. The plant was known and appreciated now in all major countries of ancient Europe and Africa - in Rome, Greece and Egypt. Today it is cultivated widely in Spain, France, Germany, Switzerland, Brazil and the southern United States. Cynara name comes from the Latin word Cinara, borrowed from the Greek (Kinara), meaning the prickly plant. Also, the second part of the name, Latin scolymus, comes from the Greek skolos, or blade. Part of the plant are edible flower shoots, thinned from July to first frosts. Suitable for consumption flower shoots well educated, with a minimum diameter of 6 - 8 cm But shortly before that when they start to grow, because the open and dark no longer fit to eat. Edible are also bleached petioles. These prized artichoke edible parts do not contain bitter compounds that are present in the leaves and stem odziomkowych used for many years in therapy. Over the centuries, although mentioned by him in his work by Pliny the Elder and Galen (ca. 130-ca. 200), an artichoke was known only as a vegetable for the elect. The first report of its valuable medicinal properties from the year 1716, when Alexander Nicholas, a monk of the Benedictine Order concluded that the use of artichoke leaf gives good results in the treatment of jaundice. In the nineteenth century, artichoke has been used in folk medicine as a means for the treatment of ascites water and rheumatic disorders. However, the greatest success in the treatment of artichoke began after World War II. Last twenty years is the time intensify scientific research in the field of Phytochemistry, pharmacology, toxicology and clinical studies on this species. The result of these studies confirm the therapeutic effectiveness of Cynara scolymus, medicinal preparations were marketed. Active substances, which owes its artichoke valuable properties Treatment can be divided into four main groups. The first is making up about 2% of the fraction of phenolic acids, containing the most important compound as a raw material cynaryna acid (1,5-dikawoilochninowy). Another group of compounds are flavonoids, derivatives luteoliny, including cynarozyd, or luteolino-7 glucoside. Another group of active compounds are sesquiterpene lactones, derivatives guaianolidowe (cynaropikryna and cynarolid), which are potent goryczami. In karczochu triterpenes are also present, among whom may be mentioned taraxasterol, stigmasterol and beta-sitosterol. Such a big group of active substances are responsible for multidirectional pharmacological activity. Extracts from the plants act żółciotwórczo (cholereticum), stimulating the liver cells to increase production of cholesterol, and then converting it into bile acids, which are the main components of bile. Acting relaxant effect on the gallbladder and bile ducts, operate cholagogic (cholagogum). In this case, the artichoke is a very valuable drug, because the increased flow of bile from 127% to 150%. Do not forget the protective effect on liver cells (hepatoprotectivum remedy), as confirmed in numerous studies both in human hepatocytes, as well as animal, carried out in vitro and in vivo. If we add to this effect antycholesterolowe (hipocholesterolemicum remedy), especially for lower levels of LDL (so-called bad cholesterol), it is not surprising that the therapeutic effects of extracts are combined with acids, mono-and di-kawoilochinowymi - cynaryną and phenol - coffee and chlorogenic . It is also important that the administration of equivalent experimental animals, in relation to the content in the extract, the dose of chlorogenic acid did not lead to a protective effect żółciopędnym whether the liver, which was confirmed not only biochemical but also pathological. This indicates that although the derivatives of caffeic acid have a significant impact on the healing properties of leaves of artichokes, but this alone is not administered therapeutically effective. This favorable characteristic phenomenon of the entire team of active substances derived from medicinal plants, rather than individual, isolated the substance, he argues about the mysterious nature of genius and still little knowledge of the composition of these extracts. Action Bile Artichoke Commission E concluded by recommending the use of its preparations in chronic liver and gall bladder, in an amount of 3 g day.
Preparations: CYNAREX, DIGESTIOL, artichoke and other

Extract Boldo orcish

Orc dwupiennym Boldo is a shrub or tree with thin branches with heart-shaped leaves naprzeciwległymi strongly aromatic. It occurs in parts of Chile and Peru on the mountain slopes. Medicinal raw material are listed.

active compounds in the leaves Boldo Orczy:

- a group of alkaloids aporfinowych (0.2% -0.5%) - about 12 compounds, mainly boldyna, leurotetanina and laurolitsina

- a group of flavonoids (0.1%) - including peumozyd, boldozyd, fragozyd

- essential oil (2% -3%) contain substantial amounts of cinerolu, askarydolu and cymolu.

Boldyna - the main ingredient of the medicinal Orczy Boldo

ABC knowledge boldynie
Boldyna, or 2,6-dihydroxy-3 ,5-dimetoksyaporfina is the main alkaloid in the leaves Boldo Orczy - Peumus boldus. This substance was isolated in 1872
by Bourgoin. Published many years researching this compound showed that it has the following properties:

medicinal properties boldyny:

- bile (cholereticum), because it stimulates hepatocytes to increase hepatic production of bile;

- diastolic (antispasmodicum) - on the smooth muscles, particularly in the bile duct and intestinal tract;

- hepatoochronne (hepatoprotectivum) - protecting the hepatic parenchyma from internal toxins and the harmful oxygen free radicals. This antioxidant effect is strong enough to protect the liver, because the body is subject boldyna pharmacokinetic first-order processes, as given orally is rapidly resorbed and preferentially accumulates in the liver, where it reaches an effective concentration;

- Diuretics (diureticum) - increases the volume of urine, along with it soluble in water environment necessary metabolic compounds - including al. uric acid.

Dosage:
boldyny daily dose is 3-4 mg, divided into portions. Boldyna is used as the active ingredient in preparations of liver and gastro-intestinal tract, usually in combination with other substances interacting synergistically.

therapeutic effect of extracts from the Orc Boldo:

a. bile and diastolic blood pressure;
effect on the gallbladder and bile ducts and sphincter Oddiego in the duodenum, facilitating the flow bile to the intestine;

b. Stimulating appetite (stomachicum);
performance by increasing the secretion of gastric juice and bile flow following stimulation of action digestion and absorption of fatty substances and other fat-soluble compounds (such as certain vitamins, cholesterol);

c. diuretic (diureticum);
action is dependent on the presence of flavonoids in the raw material and essential oil, which is strong disinfectants on the properties of the urinary tract. Only the alcoholic extracts of leaves contain essential oil orcish.

d. Scope of the medicinal product:
Orczy Boldo extracts are used in a weakened liver function, reduced ability to produce the necessary quantities of bile, gall bladder operations weakening, dyskinezie biliary and gastrointestinal symptoms after removal of the gallbladder, and in a variety of symptoms suggestive of dyspepsia - including bloating, abdominal pain, belching, bad taste in the mouth, nausea.

e. Dosage Boldo extracts Orczy:
According to the German Commission E daily intake of leaves is orcish 3 g or equivalent amount of milk. The contraindications are: sensitivity to ingredients, biliary obstruction, renal failure and acute inflammation and ulceration of the stomach and intestines.

Combination preparations: BOLDOVERA (boldyna, alony dry extract, dry extract of the herb smokebox) BOLDALOIN (dry extract of the herb smokebox, boldyna).

long extract curcuma (turmeric)

Turmeric is a plant widely used as a cooking spice turmeric Curcuma longa. Less well-known name of this plant, belonging to the ginger family Zingiberoceae is curcuma long. This is one of the most famous raw spices, originating from Asia, mainly used as an ingredient in curry. The rhizome of turmeric contains the main body of the active curcumin, which is the dominant compound in a mixture of yellow dyes kurkuminoidów. The raw material are also present essential oil (in its composition bisabolen, gwajan, zingiberen, ksantorizal, kurkumen and turmeron), starch, mineral salts and acid Ferulic, a breakdown product of curcumin, which is its dimeric derivative. Curcumin is used as a stomachic № medicine, as it stimulates the hepatic parenchyma to increased secretion of bile and facilitates the flow of bile, which prevents the formation of gallstones. Measure raw complementary anti-inflammatory properties and antioxidant properties. The rhizome of turmeric prevents metastasis through inhibition of metalloproteinases and tissue inhibitors increase the level of these enzymes. There is also a factor in angiogenesis agent, because it inhibits transcription of the two main factors, taking participation in the process of creating new blood vessels that supply the growing tumor, or vascular endothelial growth factor VEGF and bFGF (fibroblast growth factor). In addition, prevents the initiation of angiogenesis, by reducing the concentration of NO in blood vessels. An additional advantage, making it appealing for the use of turmeric rhizomes in anticancer therapy is the low toxicity, which is characterized by a raw material.

Preparations: VERDI N , SOLA REN

Phospholipids from soya beans provide the basic building blocks of cell membranes without which hepatocytes could not fulfill their functions. Particularly important is the one contained in preparations of fractions of phospholipids - phosphatidylcholine, rich in polyunsaturated fatty acids to ensure the proper structure and biophysical properties of cell membranes and lipoproteins transport fats in the blood and lowering triglycerides (an anti). Moreover, it is a precursor of important biological molecules. Indications for the use of such preparations are all kinds of liver damage (caused by alcohol, some drugs or toxic substances, and the result of having suffered infectious jaundice), and cholelithiasis and functional impairment of bile ducts. There are also work indicating that they may have a protective effect in some inflammatory gastrointestinal tract. Medicines containing phospholipids are safe to use, does not interact with other drugs and do not accumulate in the body. Adverse reactions that can cause, usually limited to mild disorders of the gastrointestinal tract.

Preparations: ESSELIV FORTE, FORTE ESSENTIAL.

amino acids (mainly L-arginine and L-ornithine, thiazolidin acid converts the L-cysteine) accelerate detoxification processes, supporting the process of synthesizing urea from ammonia and favorably affect the metabolism of proteins , fat and carbohydrates in the body. High concentrations of ammonia poisons the body, preventing the energy metabolism and reduces brain activity. Positive effects of the protective effect of arginine and ornithine are particularly important in the case of living in a polluted environment, alcohol and large quantities of drugs (particularly anti-cancer, antituberculous).

Preparations: HEPATIL, HEPATENAL MAX , HEPA BALANCE

Combination preparations:

Raphacholin C (extract of artichoke, dehydrocholic acid, peppermint oil, dry extract of black radish root, activated carbon)

Raphacholin FORTE (dry extract black radish root, peppermint oil, acid dehydrocholic)

Verdin COMPLEX (artichoke extract, rosemary extract)

SYLIMAFORT, HEPATOBON (extract of artichoke extract, milk thistle seed)

GASTROBON (extract from the root and herb dandelion, artichoke extract)

is also preferred the use of formulas enriched with B vitamins: B 1, B 2, B 6 and PP - are important in normal metabolic processes such as

SYLIVIT, LIVIT (extract from milk thistle, vitamin)

HEPATIL VIT (amino acids, vitamins)

Doppelherz ACTIV the liver (extract of artichoke, omega-3 fatty acids, vitamins)

HEPASON COMPLEX (extract of artichoke, vitamins)

How to prevent and treat diseases of the liver and gall bladder?

· dyspepsia (indigestion) associated with a deficiency of bile (difficult absorption of fat, flatulence, constipation) - Preparations Bile, bile, relaxant action (combinations work best), for example BOLDOVERA, SYLIMAFORT, hepato PROTECT HEPATOBON, GASTROBON

· ; inflammation of bile ducts and gallbladder, gallstones, and the associated biliary colic, cholecystectomy - Bile and bile preparations provided the permeability of the bile ducts, (recommended preparations are complex and contain vitamins) such BOLDOVERA, SYLIMAFORT, hepato PROTECT HEPATOBON, GASTROBON, HEPATIL VIT, Doppelherz ACTIV, HEPASON and preparations of phospholipids and amino acids such as ESENTIALE FORTE, FORTE ESSELIV, HEPATIL ESS

· toxic and drug-induced liver injury (eg postalcohol liver damage), chronic hepatitis, steatosis and cirrhosis of the liver - preparations of phospholipids and amino acids such as ESSENTIAL FORTE, FORTE ESSELIV, HEPATIL

· prophylaxis (bodybuilding diet, high protein) and during convalescence after diseases of liver - phospholipid preparations and amino acids such as ESSENTIAL FORTE, FORTE ESSELIV, HEPATIL, HEPATILVIT

How to use preparations containing substances to support my liver?

Always read the leaflet included with the product and follow the information contained therein. Preparations should not be used after expiry date.

preparation of the action and żółciotwórczym żółciopędnym best used after a meal, usually temporarily, in case of complaints. Does not apply to patients after surgery to remove gall bladder (cholecystectomy), which should use these drugs chronically.

For the effect of liver regeneration, it is necessary preparations for a regular intake of at least 2-3 months (in the case of phospholipids up to 12 months) at doses provided by the manufacturer for a particular disease or prescribed by a doctor . Prolonged use of assistive liver preparations, while maintaining the recommended dosage, not associated with the occurrence of life-threatening side effects. It is even necessary, since the use of smaller doses or taking a shorter time will not achieve the expected benefits.

How should eat people with liver disease?

should be to minimize the intake of animal fat, spices, certain vegetables and fruits and alcohol. Diet should be rich in protein and carbohydrates.
To avoid unpleasant symptoms as bloating or reflection it is divided into smaller meals instead of 3 and 5 meals to eat.

Milk and dairy products contain valuable protein, but some of its products (such as yellow or melted cheese, blue cheeses, butter and cream) is rich in fats and their consumption may be a cause of pain in patients with cholelithiasis. Therefore, it is better to drink skimmed milk (ie 0% fat), low fat cottage cheese, yogurt and kefir.

in patients with liver disease is contraindicated eating greasy pork, smoked meats and canned fish and high in fat and hot spices. The best eat meat products, poultry and veal or lean pork in the form of cooked, baked or stewed. Do not eat meat fried in fat and battered.

complaints from the liver may also occur after eating cake with cream, cakes and chocolate. However, you can eat small amounts of biscuits, cookies and biscuits and jelly.

contraindicated with vegetables are cabbage, onion, garlic, peas and beans on the fruits of pears and plums. Other Fruit is best eaten in the form of purees, juices, well without the addition of shredded salad cream or mayonnaise. Often, abdominal distension and pain symptoms in patients with cholelithiasis are not caused by eating vegetables, but the additives used to them just like mayonnaise or cream, or hot spices. You can also cook vegetables steamed or boiled and eaten as cooked without added butter.